Semantic Map for Structural Bioinformatics

BioNavigation was the first prototype developed in collaboration with Louiqa Raschid and Maria Esther Vidal, University of Maryland , College Park . The motivations of the projects were to develop a system that would support resource discovery as well as cost prediction. The characteristics of BioNavigation are the following.

·         The resources stored in the semantic map are interlinked data sources;

·         The ontology is a simple graph where each node represents a scientific object (e.g., gene) and an edge between two nodes denotes the relationship between two scientific objects;

·         Each resource is mapped to the scientific object(s) it provides information about (e.g., GenBank is mapped to the ontology class Sequence);

·         Each link (index, hyperlink, etc.) linking two resources is an instance of the edge linking the two corresponding scientific objects;

·         The cardinality of each data source as well as the domain, range, and cardinality of links are stored as metadata in the semantic map;

·         Resource discovery queries are path expressions on the ontology;

·         Users may select a semantics to predict the cost of physical path (e.g., return the resources more likely to return as many entries as possible);

·         Answers of a resource discovery query are a list of physical paths ranked with respect to the selected semantics.


Prototypes

Publications related to BioNavigation are listed in the project Web site. The software can be downloaded below. It comes with a demonstration semantic map that needs to be updated by the user. The following updates are needed:

·          Update of ontology

·          Entry of resources

·          Mapping to ontology

·          Identification of metadata

·          Entry of metadata

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BioNavigation Software Download

(Installation Requirements:
At least 25MB of disk space for the program folder)

 

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Download Installation Instructions for BioNavigation prototype interface
(.pdf)

Scientific Data Management Lab


      
emantic Map for Structural bioinformatics Semantic Map for Structural Bioinformatics BioMobyMap

Under Progress

BioNavigation was a first system aiming at supporting resource discovery. Its development and its limitations were used to design a new approach to develop semantic maps for resource discovery.

Resources – BioNavigation focused on federated data sources. The new approach includes scientific applications (e.g., BLAST).

Ontology – The ontology in BioNavigation is limited to linked scientific objects. The new approach aims at capturing various scientific relationships. The resulting ontology is a complex graph with directed labeled multi-edges and a isa hierarchy.

Exploring the semantic mapBioNavigation displays the whole semantic map (see below).  The current approach aims at capturing all existing resources, therefore visualization strategies need to be designed.

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Querying the semantic map – Queries in BioNavigation are path expressions against the semantic map. The new approach aims at expressing scientific workflows.

Metadata – Metadata such as resource cardinality as typically not published by resource providers. There are difficult to locate or compute. The new approach does not capture these quantitative metadata for now.

Service registration – No service registration was designed for BioNavigation. We aim at automating the registration of resources for the new verion.


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